Endocrine Abstracts

Women with polycystic ovary syndrome (PCOS) have twice the risk for metabolic syndrome (MetS) compared to women from the general population. Mothers and sisters of affected women also have an increased prevalence of MetS. We undertook this study to evaluate whether these abnormalities are also present in brothers’ of affected women.Design and setting: A total of 59 brothers (age ≥18 and ≤40 years) of women with PCOS and 59 healthy men (o...

Background and aims: Proper assessment of long-term safety of newer antidiabetic agents (ADAs) is of prime importance as diabetes is a chronic disease requiring life-long management. The purpose of this analysis was to assess the safety of vildagliptin as monotherapy or as an add-on therapy to already existing ADAs (vildagliptin group) compared to non-vildagliptin group.Materials and methods: Nine hundred and eighty-three patients in vildagliptin group a...